Scientist found the solution for hair growth, with the help of human pluripotent stem cells.
Alexey Terskikh, an associate professor at Sanford-Burnham Medical Research Institute (Sanford-Burnham) says that they had developed a new method to create new cells of initiating human hair growth with the help of human pluripotent stem cells and was a marked improvement over current methods that rely on transplanting existing hair follicles from one part of the head to another.
The method of the stem cells provides a limitless source of cells from the patient for transplantation and wasn’t limited by the availability of existing hair follicles.
The team of researchers developed a protocol that coaxed human pluripotent stem cells to become dermal papilla cells. These cells are unique populations that are regulating hair-follicle formation and growth cycle.
Sometimes human Dermal Papilla cells are not suitable in hair transplants because of they cannot be obtained in necessary amounts and rapidly lose their ability to induce hair-follicle formation in culture.
Terskikh said “We developed a protocol to drive human pluripotent stem cells to differentiate into dermal papilla cells and confirmed their ability to induce hair growth when transplanted into mice,” and also added “Our next step is to transplant human dermal papilla cells derived from human pluripotent stem cells back into human subjects.”